Western Blot Positive WB detected in: MCF-7 whole cell lysate, Rat brain tissue, Rat heart tissue, Mouse brain tissue, Mouse heart tissue, Mouse kidney tissue All lanes: DKC1 antibody at 2.5microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 58, 48 kDa Observed band size: 48 kDa

DKC1 Antibody

CSB-PA006919LA01HU

ApplicationsImmunoFluorescence, Western Blot, ELISA

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetDKC1

Overview

Supplier
Cusabio
Product Name
DKC1 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID1736
Target name
DKC1
Target description
dyskerin pseudouridine synthase 1
Target synonyms
CBF5; CBF5 homolog; DKC; DKCX; dyskeratosis congenita 1, dyskerin; H/ACA ribonucleoprotein complex subunit 4; H/ACA ribonucleoprotein complex subunit DKC1; NAP57; NOLA4; nopp140-associated protein of 57 kDa; nucleolar protein family A member 4; nucleolar protein NAP57; snoRNP protein DKC1; XAP101
Host
Rabbit
Isotype
IgG
Protein IDO60832
Protein Name
H/ACA ribonucleoprotein complex subunit DKC1
Scientific Description
Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (psi) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

DKC1 Antibody

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Overview