DKC1 blocking peptide

GeneTex

DKC1 blocking peptide

9

Research Use Only

DKC1

dyskerin pseudouridine synthase 1

CBF5, CHINE1, DKC, DKCX, NAP57, NOLA4, XAP101, H/ACA ribonucleoprotein complex subunit DKC1, CBF5 homolog, H/ACA ribonucleoprotein complex subunit 4, dyskeratosis congenita 1, dyskerin, nopp140-associated protein of 57 kDa, nucleolar protein NAP57, nucleolar protein family A member 4, snoRNP protein DKC1

This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

-20°C or -80°C,2°C to 8°C

41116100

Human