DKK-1, Mouse (HEK293, His)

MedChem Express

DKK-1, Mouse (HEK293, His)

10

Research Use Only

98.0

Dkk1

dickkopf WNT signaling pathway inhibitor 1

dickkopf homolog 1; dickkopf-1; dickkopf-like protein 1; dickkopf-related protein 1; dkk-1; mdkk-1

Dickkopf-related protein 1

DKK-1 protein antagonizes canonical Wnt signaling by inhibiting LRP5/6-Wnt interaction and forming a ternary complex with KREMEN, thereby promoting LRP5/6 internalization. In addition to its Wnt-dependent role, DKK1 has Wnt-independent anti-apoptotic activity by inhibiting the pro-apoptotic function of KREMEN1. DKK-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DKK1 protein, expressed by HEK293 , with C-His labeled tag.

-20°C

41116100