DLK-IN-1 [1620574-24-4]

TargetMol Chemicals

DLK-IN-1 [1620574-24-4]

114

1620574-24-4

Chemical

Research Use Only

DLK-IN-1

C20H24F3N5O2

423.43

DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. DLK-IN-1 is active in the Alzheimers disease model, retains excellent CNS permeability, and after multiple days of administration, its concentration exceeds the concentration required for DLK inhibition in the brain, so it has good tolerance Acceptability.

3 years

[H][C@@]12CN(C[C@]1([H])[C@H]2c1cc(nn1C(C)C)-c1cnc(N)c(OC(F)(F)F)c1)C1COC1

-20°C

51202000