Bio-Connect

DM4-SMe

HY-130082
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DM4-SMe [796073-68-2]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    DM4-SMe is a metabolite of antibody-maytansin conjugates (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs) , which can be linked to antibody through disulfide bond or stable thioether bond. DM4-SMe inhibits KB cells with an IC 50 of 0.026 nM [1] [2] .
  • Storage Instruction
    -20°C
  • UNSPSC
    41116133