Western blot analysis of extracts of various cell lines using DMAP1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using DMAP1 Polyclonal Antibody at dilution of 1:1000.
DMAP1 Polyclonal Antibody
E-AB-62489
Product group Antibodies
Overview
- SupplierElabscience
- Product NameDMAP1 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
- UNSPSC12352203