DMAP1 Polyclonal Antibody

Reddot Biotech

DMAP1 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

DMAP1

DNA methyltransferase 1 associated protein 1

DNA methyltransferase 1-associated protein 1; DNMAP1; DNMT1 associated protein 1; DNMTAP1; EAF2; MEAF2; SWC4

Rabbit

IgG

This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

Human, Mouse, Rat

-20°C

12352203