DMBA-SIL-Mal-MMAE

MedChem Express

DMBA-SIL-Mal-MMAE

5

Research Use Only

99.79

C72H106N8O20

1403.65

DMBA-SIL-Mal-MMAE is a cytotoxin-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked DMBA-SIL-Mal[1].

O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OC(C3=CC=C(C=C3)NC(OCC4=CC(OC)=CC(OC)=C4)=O)C(NCCOCCOCCOCCOCCN5C(C=CC5=O)=O)=O)=O)=O)=O)=O)OC)=O

-20°C

41115800