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DMC1 antibody

GTX11054
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetDMC1
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Overview

  • Supplier
    GeneTex
  • Product Name
    DMC1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    For IF: Suggested starting dilution 1:100. Fix cells using a 4% paraformaldehyde solution and permeabilize using SDS (0.03% in a 4% paraformaldehyde solution). Incubate antibody overnight. For IP: Use at an assay dependent dilution. For WB: Suggested starting dilution 1:200. Predicted molecular weight: 41 kDa. Optimal dilutions/concentrations should be determined by the end user.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Concentration
    0.7 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID11144
  • Target name
    DMC1
  • Target description
    DNA meiotic recombinase 1
  • Target synonyms
    DMC1H, LIM15, dJ199H16.1, meiotic recombination protein DMC1/LIM15 homolog, DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination, disrupted meiotic cDNA1, yeast, homolog of
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDQ14565
  • Protein Name
    Meiotic recombination protein DMC1/LIM15 homolog
  • Scientific Description
    This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chang HY, Lee CY, Lu CH, et al. Microcephaly family protein MCPH1 stabilizes RAD51 filaments. Nucleic Acids Res. 2020,48(16):9135-9146. doi: 10.1093/nar/gkaa636
    Read this paper