DMC1 antibody

GeneTex

DMC1 antibody [2H12/4]

9

Specific for DMC1 - does not cross-react with the related protein Rad51.

For IF: Suggested starting dilution 1:100. Fix cells using a 4% paraformaldehyde solution and permeabilize using SDS (0.03% in a 4% paraformaldehyde solution). Incubate antibody overnight. For IP: Use at an assay dependent dilution. For WB: Suggested starting dilution 1:200. Predicted molecular weight: 41 kDa. Optimal dilutions/concentrations should be determined by the end user.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

0.7 mg/ml

Unconjugated

Liquid

DMC1

DNA meiotic recombinase 1

disrupted meiotic cDNA1, yeast, homolog of; dJ199H16.1; DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination; DMC1H; LIM15; meiotic recombination protein DMC1/LIM15 homolog

Mouse

IgG2a

Meiotic recombination protein DMC1/LIM15 homolog

This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Bovine, Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203