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ProductsBack/DMX-5804 [2306178-56-1]

DMX-5804 [2306178-56-1]

Research Use Only
HY-111754
MedChem Express
CAS Number2306178-56-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.83
Molecular Weight361.39
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DMX-5804 [2306178-56-1]
  • Delivery Days Customer
    10
  • CAS Number
    2306178-56-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.83
  • Molecular Formula
    C21H19N3O3
  • Molecular Weight
    361.39
  • Scientific Description
    DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96). DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice[1].
  • SMILES
    O=C1NC=NC2=C1C(C3=CC=C(OCCOC)C=C3)=CN2C4=CC=CC=C4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200