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ProductsBack/DNA ligase I antibody [C2C3], C-term

Sample (30 ug of whole cell lysate) A: A431 (GTX27909) B: H1299 7.5% SDS PAGE GTX102936 diluted at 1:1000

Sample (30 ug of whole cell lysate) A: A431 (GTX27909) B: H1299 7.5% SDS PAGE GTX102936 diluted at 1:1000

Sample (30 ug of whole cell lysate) A: A431 (GTX27909) B: H1299 7.5% SDS PAGE GTX102936 diluted at 1:1000

DNA ligase I antibody [C2C3], C-term

GTX102936

ApplicationsWestern Blot

Product group Antibodies

ReactivityHuman

TargetLIG1

Overview

Supplier
GeneTex
Product Name
DNA ligase I antibody [C2C3], C-term
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID3978
Target name
LIG1
Target description
DNA ligase 1
Target synonyms
IMD96, LIGI, hLig1, DNA ligase 1, ligase I, DNA, ATP-dependent, polydeoxyribonucleotide synthase [ATP] 1
Host
Rabbit
Isotype
IgG
Protein IDP18858
Protein Name
DNA ligase 1
Scientific Description
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq]
Reactivity
Human
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Liddiard K, Ruis B, Kan Y, et al. DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase. Nucleic Acids Res. 2019,47(5):2402-2424. doi: 10.1093/nar/gky1279
Read this paper
Valdez BC, Li Y, Murray D, et al. The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells. Leuk Lymphoma. 2017,58(11):2705-2716. doi: 10.1080/10428194.2017.1306647
Read this paper

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