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ProductsBack/DNA ligase I antibody [C2C3], C-term

DNA ligase I antibody [C2C3], C-term

Research Use Only
GTX102936
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetLIG1
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Packing Size
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    GeneTex
  • Product Name
    DNA ligase I antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3978
  • Target name
    LIG1
  • Target description
    DNA ligase 1
  • Target synonyms
    DNA ligase 1; ligase I, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase. Liddiard K et al., 2019 Mar 18, Nucleic Acids Res
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  • The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells. Valdez BC et al., 2017 Nov, Leuk Lymphoma
    Read more