DNA2 inhibitor C5

MedChem Express

DNA2 inhibitor C5 [35973-25-2]

10

35973-25-2

Research Use Only

98.51

C10H6N2O5

234.17

DNA2 inhibitor C5 is a potent, competitive and specific inhibitor of DNA2 nuclease activity with an IC 50 of 20 microM. DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2. DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress [1] .

O=C(C1=C(O)C2=CC=CC([N+]([O-])=O)=C2N=C1)O

-20°C,2°C to 8°C

12352200