DnaK Mix

Cosmo Bio USA

DnaK Mix

16

Research Use Only

DnaK Mix is a newly developed supplement for the PUREfrex® series reconstituted coupled transcription/translation systems, designed to promote proper folding and improve solubility for proteins that require molecular chaperones for proper folding. It comprises an optimized ratio of highly purified E.coli-derived DnaK, DnaJ and GrpE. DnaK Mix is a newly developed supplement for the PUREfrex® series, designed to assist proper folding and improve solubility of proteins that require molecular chaperones for proper protein folding. DnaK Mix comprises an optimized ratio of highly purified E.coli-derived DnaK, DnaJ and GrpE. ATPase activity of DnaK (Hsp70) is stimulated by co-chaperones DnaJ and GrpE. DnaJ promotes the ATPase activity of DnaK and can bind to hydrophobic regions of synthesized proteins. GrpE stimulates ADP/ATP exchange rate of DnaK. Chaperone Supplement DnaK Mix comprises highly purified and ratio-optimized E. coli DnaK, DnaJ and GrpE. DnaK, known as Hsp70, has ATPase activity and is stimulated by co-chaperones DnaJ and GrpE. DnaJ facilitates DnaK ATPase activity and binds to hydrophobic regions of synthesized proteins. GrpE stimulates ADP/ATP exchange of DnaK. DnaK Mix works well with PUREfrex®series and DsbC Set. Chaperone Supplement GroE Mix comprises highly purified and ratio-optimized E. coli GroEL (known as Hsp60) and GroES (works in conjunction with GroEL).

-80°C

41106200