The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA045438(DNASE1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA045438(DNASE1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200)
DNASE1 Antibody
CSB-PA045438
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDNASE1
Overview
- SupplierCusabio
- Product NameDNASE1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1773
- Target nameDNASE1
- Target descriptiondeoxyribonuclease 1
- Target synonymsDNL1, DRNI, deoxyribonuclease-1, DNase I, lysosomal, Dornase alfa, deoxyribonuclease I, human urine deoxyribonuclease I
- HostRabbit
- IsotypeIgG
- Protein IDP24855
- Protein NameDeoxyribonuclease-1
- Scientific DescriptionThis gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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