Docetaxel (Trihydrate)
HY-B0011A
Overview
- SupplierMedChem Express
- Product NameDocetaxel (Trihydrate) [148408-66-6]
- Delivery Days Customer10
- CAS Number148408-66-6
- CertificationResearch Use Only
- Estimated Purity99.92
- Molecular FormulaC43H59NO17
- Molecular Weight861.93
- Scientific DescriptionDocetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC 50 value of 0.2 microM [1] . Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis [1] [3] .
- SMILESO=C(OC(C)(C)C)N[C@H]([C@H](C(O[C@@H]1C(C)=C([C@@H](O)C([C@@]2(C)[C@]([C@@](CO3)(OC(C)=O)[C@@]3([H])C[C@@H]2O)([H])[C@@H]4OC(C5=CC=CC=C5)=O)=O)C(C)(C)[C@@]4(O)C1)=O)O)C6=CC=CC=C6.O.O.O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200