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Docetaxel (Trihydrate)

HY-B0011A
MedChem Express
CAS Number148408-66-6
Product group Chemicals
Estimated Purity99.92
Molecular Weight861.93
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Docetaxel (Trihydrate) [148408-66-6]
  • Delivery Days Customer
    10
  • CAS Number
    148408-66-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.92
  • Molecular Formula
    C43H59NO17
  • Molecular Weight
    861.93
  • Scientific Description
    Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC 50 value of 0.2 microM [1] . Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis [1] [3] .
  • SMILES
    O=C(OC(C)(C)C)N[C@H]([C@H](C(O[C@@H]1C(C)=C([C@@H](O)C([C@@]2(C)[C@]([C@@](CO3)(OC(C)=O)[C@@]3([H])C[C@@H]2O)([H])[C@@H]4OC(C5=CC=CC=C5)=O)=O)C(C)(C)[C@@]4(O)C1)=O)O)C6=CC=CC=C6.O.O.O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200