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ProductsBack/DOCK3 Antibody

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA818270LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA818270LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA818270LA01HU at dilution of 1:100

DOCK3 Antibody

CSB-PA818270LA01HU

ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetDOCK3

Overview

Supplier
Cusabio
Product Name
DOCK3 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID1795
Target name
DOCK3
Target description
dedicator of cytokinesis 3
Target synonyms
MOCA, NEDIDHA, PBP, dedicator of cytokinesis protein 3, modifier of cell adhesion, presenilin-binding protein
Host
Rabbit
Isotype
IgG
Protein IDQ8IZD9
Protein Name
Dedicator of cytokinesis protein 3
Scientific Description
Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (By similarity).
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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