Dopamine D4 receptor ligand 3
HY-173431
Molecular Weight489.56
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameDopamine D4 receptor ligand 3
- Delivery Days Customer999
- CertificationResearch Use Only
- Molecular FormulaC28H31N3O5
- Molecular Weight489.56
- Scientific DescriptionDopamine D4 receptor ligand 3 (Compound 16) is a dopamine D4 receptor (D4R) antagonist (pKi: 8.86). Dopamine D4 receptor ligand 3 has pIC50 values of 5.78, 5.55, and 6.17 for Go, Gi, and betaArr2 sensors in HEK-293T cells, respectively. Dopamine D4 receptor ligand 3 inhibits the viability of three human glioma cell lines, U87 MG, T98G, and U251 MG. Dopamine D4 receptor ligand 3 induces ROS production and mitochondrial dysfunction in glioma cells[1].
- SMILESO=C(CCC1=C2C=CC=C1)N2CCCN3CCN(CC3)C4=CC=C5C=CC=CC5=C4.O=C(O)C(O)=O
- UNSPSC12352200