Doravirine

AbMole BioScience

Doravirine

9

1338225-97-0

Chemical

Research Use Only

C17H11C1F3N5O3

425.75

Doravirine (MK-1439) is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay.

CN1C(=O)NN=C1CN2C=CC(=C(OC3=CC(=CC(=C3)C#N)Cl)C2=O)C(F)(F)F

12352200