DOV-216,303

MedChem Express

DOV-216,303 [86215-36-3]

14

86215-36-3

Research Use Only

C11H12Cl3N

264.58

DOV-216,303 is an antidepressant compound. DOV-216,303 inhibits the reuptake of norepinephrine (NE), serotonin (5-HT), and dopamine (DA), with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. DOV-216,303 increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats[1][2][3].

ClC1=C(C=C(C23CC2CNC3)C=C1)Cl.Cl

12352200