Doxofylline

MedChem Express

Doxofylline [69975-86-6]

10

69975-86-6

Research Use Only

99.65

C11H14N4O4

266.25

Doxofylline is an orally active PDE IV inhibitor and A1AR antagonist. Doxofylline reduces inflammation in epithelial cells via inhibiting mitochondrial ROS production and amelioration of multiple cellular pathways ( NLRP3-TXNIP inflammasome activation). Doxophylline can be used in studies of asthma, chronic obstructive pulmonary disease, and bronchospasm [1] [2] [3] .

O=C(N1C)N(C)C2=C(N(CC3OCCO3)C=N2)C1=O

-20°C,2°C to 8°C

12352200