DPA [131-73-7]

Biotium

DPA

9

131-73-7

Research Use Only

00079,1.1d,ghs01 unstable, expolosive ghs06 toxic ghs08 systemic health hazards ghs09 environment,h201 explosive; mass explosion hazard. h300 fatal if swallowed., h310 fatal in contact with ...

Dipicrylamine (DPA) is a nonfluorescent anionic membrane dye. With its absorbance in the blue region of the visible spectrum, DPA can be used as a FRET quencher for a variety of fluorescent donor dyes. When applied to cells, DPA localizes at the interface of cytoplasmic membrane and aqueous phase in a manner sensitive to membrane potential change. A recent application of DPA is to measure cell membrane potential change by combining with the fluorescent donor dye DiOC16. The DiO/DPA system has been reported to produce a fluorescence signal change of >56% in HEK-293 cells and >25% in neuronal cultures and brain slices per 100 mV membrane potential change. Please also see the DiO/DPA Membrane Potential Detection Kit. Yellow solid soluble in DMSO at >30mg/mL lambdaabs (MeOH) = 406 nm Store at 4°C MWt: 439.21 [131-73-7]

Synthetic

2°C to 8°C

41116134