DPM [143503-03-1]

Chemodex

DPM [143503-03-1]

10

143503-03-1

Research Use Only

>97%

C20H16N2O5

364.35

Chemical. CAS: 143503-03-1. Formula: C20H16N2O5. MW: 364.35. Synthetic. Nonfluorescent N-substituted maleimides react selectively with thiol compounds to form fluorescent derivatives. Fluorescent intensity of the dimethoxyphthalimidyl group is higher than that of the nonsubsituted phthalimidyl group. The analytical sensitivity of N-[4-(5,6-Dimethoxy-N-phthalimidyl)phenyl]maleimide (DPM) is about 3-times higher than that of N-[4-(2-phthalimidyl)phenyl]maleimide (PPM). DPM can be used as a precolumn labeling reagent in HPLC. DPM was also used for the determination of physiologically important thiols in biological fluids or therapeutic drug monitoring. - Nonfluorescent N-substituted maleimides react selectively with thiol compounds to form fluorescent derivatives. Fluorescent intensity of the dimethoxyphthalimidyl group is higher than that of the nonsubsituted phthalimidyl group. The analytical sensitivity of N-[4-(5,6-Dimethoxy-N-phthalimidyl)phenyl]maleimide (DPM) is about 3-times higher than that of N-[4-(2-phthalimidyl)phenyl]maleimide (PPM). DPM can be used as a precolumn labeling reagent in HPLC. DPM was also used for the determination of physiologically important thiols in biological fluids or therapeutic drug monitoring.

COC1=C(OC)C=C2C(CN(C2=O)C2=CC=C(C=C2)N2C(=O)C=CC2=O)=C1

2°C to 8°C,-20°C

12352200