DPM1 antibody

GeneTex

DPM1 antibody

9

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

DPM1

dolichyl-phosphate mannosyltransferase subunit 1, catalytic

CDGIE; dolichol monophosphate mannose synthase; dolichol-phosphate mannose synthase subunit 1; dolichol-phosphate mannosyltransferase subunit 1; dolichyl-phosphate beta-D-mannosyltransferase subunit 1; dolichyl-phosphate mannosyltransferase polypeptide 1 catalytic subunit; DPM synthase complex, catalytic subunit; DPM synthase subunit 1; mannose-P-dolichol synthase subunit 1; MPD synthase subunit 1; MPDS

Rabbit

IgG

Dolichol-phosphate mannosyltransferase subunit 1

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203