DPQ

MedChem Express

DPQ [129075-73-6]

5

129075-73-6

Research Use Only

99.68

C18H26N2O2

302.41

DPQ is a blood-brain barrier permeable and selective PARP-1 inhibitor that blocks PARP-1-mediated DNA damage repair and NAD+/ATP consumption, thereby inhibiting excessive inflammatory responses. DPQ inhibits NF-kappaB pathway activation, reduces the expression of pro-inflammatory factors (such as TNF-alpha, IL-6) and oxidative stress. DPQ can be used in inflammation-related studies of acute lung injury, myocardial infarction, and neurodegenerative diseases[1][2][3].

O=C1C2=C(CCN1)C(OCCCCN3CCCCC3)=CC=C2

-20°C,2°C to 8°C

12352200