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DPQ (hydrochloride) [84050-22-6]

HY-W424851
MedChem Express
CAS Number84050-22-6
Product group Chemicals
Molecular Weight325.79
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DPQ (hydrochloride) [84050-22-6]
  • Delivery Days Customer
    14
  • CAS Number
    84050-22-6
  • Certification
    Research Use Only
  • Molecular Formula
    C14H20ClN5O2
  • Molecular Weight
    325.79
  • Scientific Description
    DPQ hydrochloride is a blood-brain barrier permeable and selective PARP-1 inhibitor that blocks PARP-1-mediated DNA damage repair and NAD+/ATP consumption, thereby inhibiting excessive inflammatory responses. DPQ hydrochloride inhibits NF-kappaB pathway activation, reduces the expression of pro-inflammatory factors (such as TNF-alpha, IL-6) and oxidative stress. DPQ hydrochloride can be used in inflammation-related studies of acute lung injury, myocardial infarction, and neurodegenerative diseases[1][2][3].
  • SMILES
    NC1=C2C=C(OC)C(OC)=CC2=NC(N3CCNCC3)=N1.[H]Cl
  • UNSPSC
    12352200

MSDS

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