DPTIP-prodrug 18

MedChem Express

DPTIP-prodrug 18 [2881068-33-1]

10

Research Use Only

C36H44N4O4S

628.82

DPTIP-proagent 18 (P18) is a orally active and brain-penetrable proagent of DPTIP (HY-131002). DPTIP-proagent 18 is a potent nSMase2 inhibitor. DPTIP-proagent 18 significantly inhibits IL-1beta-induced EV (extracellular vesicle) release by inhibition of nSMase2 (neutral sphingomyelinase-2) activity. DPTIP-proagent 18 can be used for brain injury research[1].

COC1=CC(C2=NC(C3=CC=CC=C3)=C(C4=CC=CS4)N2)=CC(OC)=C1OC(N5C(CC)CC(CC5CC)N6CCCCC6)=O

12131703