DQn-1 [57343-54-1]
HY-154807
CAS Number57343-54-1
Product group Chemicals
Molecular Weight343.77
Overview
- SupplierMedChem Express
- Product NameDQn-1 [57343-54-1]
- Delivery Days Customer10
- CAS Number57343-54-1
- CertificationResearch Use Only
- Molecular FormulaC16H14ClN5O2
- Molecular Weight343.77
- Scientific DescriptionDQn-1 is a potent antifolate with activity against Mycobacterium tuberculosis (Mtb) (MIC90=0.03 microM). DQn-1 directly inhibits DHFR enzyme activity, with IC50s of 8.7 and 7.6 nM for Mtb and human DHFR enzyme, respectively[1].
- SMILESO=C(C1=CC=C(NCC2=CC=C3N=C(N)N=C(C3=C2Cl)N)C=C1)O
- UNSPSC12352200