DR3/TNFRSF25, Human (HEK293, Fc)

MedChem Express

DR3/TNFRSF25, Human (HEK293, Fc)

10

Research Use Only

98.0

TNFRSF25

TNF receptor superfamily member 25

APO-3, DDR3, DR3, GEF720, LARD, PLEKHG5, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR, tumor necrosis factor receptor superfamily member 25, Guanine nucleotide exchange factor 720, PH domain-containing family G member 5, Pleckstrin homology domain-containing family G member 5, apoptosis inducing receptor, apoptosis-inducing receptor AIR, apoptosis-mediating receptor DR3, apoptosis-mediating receptor TRAMP, death domain receptor 3 soluble form, death receptor beta, lymphocyte-associated receptor of death, protein WSL-1, tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)

Tumor necrosis factor receptor superfamily member 25

DR3/TNFRSF25 Protein, the receptor for TNFSF12/APO3L/TWEAK, interacts with adapter TRADD, activating NF-kappa-B and inducing apoptosis. It may crucially regulate lymphocyte homeostasis. Forming homodimers, it strongly interacts with TNFRSF1 and TRADD via death domains, initiating distinct apoptosis and NF-kappa-B signaling cascades. Interaction with BAG4 contributes to its multifaceted cellular response roles. DR3/TNFRSF25 Protein, Human (HEK293, Fc) is the recombinant human-derived DR3/TNFRSF25 protein, expressed by HEK293 , with C-hFc labeled tag.

-20°C

41116100

Human