DR3/TNFRSF25, Human (HEK293, Fc)

MedChem Express

DR3/TNFRSF25, Human (HEK293, Fc)

10

Research Use Only

98.0

TNFRSF25

TNF receptor superfamily member 25

APO-3; apoptosis inducing receptor; apoptosis-inducing receptor AIR; apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; DDR3; death domain receptor 3 soluble form; death receptor beta; DR3; GEF720; Guanine nucleotide exchange factor 720; LARD; lymphocyte-associated receptor of death; PH domain-containing family G member 5; Pleckstrin homology domain-containing family G member 5; PLEKHG5; protein WSL-1; TNFRSF12; TR3; TRAMP; tumor necrosis factor receptor superfamily member 25; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); WSL-1; WSL-LR

Tumor necrosis factor receptor superfamily member 25

DR3/TNFRSF25 Protein, the receptor for TNFSF12/APO3L/TWEAK, interacts with adapter TRADD, activating NF-kappa-B and inducing apoptosis. It may crucially regulate lymphocyte homeostasis. Forming homodimers, it strongly interacts with TNFRSF1 and TRADD via death domains, initiating distinct apoptosis and NF-kappa-B signaling cascades. Interaction with BAG4 contributes to its multifaceted cellular response roles. DR3/TNFRSF25 Protein, Human (HEK293, Fc) is the recombinant human-derived DR3/TNFRSF25 protein, expressed by HEK293 , with C-hFc labeled tag.

-20°C

41116100