Dronedarone [141626-36-0]

MedChem Express

Dronedarone [141626-36-0]

5

141626-36-0

Research Use Only

99.93

C31H44N2O5S

556.76

Dronedarone (SR 33589), a derivative of amiodarone (HY-14187), is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone is a potent blocker of multiple ion currents, including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to beta-adrenergic receptors. Dronedarone is a substrate for and a moderate inhibitor of CYP3A4[1].

CCCCC1=C(C2=C(C=CC(NS(C)(=O)=O)=C2)O1)C(C3=CC=C(C=C3)OCCCN(CCCC)CCCC)=O

-20°C,2°C to 8°C

12352200