DS45500853

MedChem Express

DS45500853 [2735803-28-6]

10

2735803-28-6

Research Use Only

98.15

C18H20O3

284.35

DS45500853 is an estrogen-related receptor alpha (ERRalpha) agonist. DS45500853 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRalpha ligand-binding domain (LBD; 1.2 microM) with an IC50 value of 0.80 microM. DS45500853 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM)[1].

CC(C1=CC=C(OC2=CC=C(O)C(C(C)(C)C)=C2)C=C1)=O

-20°C,2°C to 8°C

12352200