DSG1 Polyclonal Antibody

Reddot Biotech

DSG1 Polyclonal Antibody

5

ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

DSG1

desmoglein 1

cadherin family member 4; CDHF4; desmoglein-1; desmosomal glycoprotein 1; DG1; DSG; EPKHE; EPKHIA; pemphigus foliaceus antigen; PPKS1; SPPK1

Rabbit

IgG

This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

Human, Rat

-20°C

12352203