DSPE-PEG2000-iRGD

MedChem Express

DSPE-PEG2000-iRGD

5

Research Use Only

95.0

2000 (Average)

DSPE-PEG2000-iRGD is a PEG compound which composed of DSPE and an alphav-integrins targeting peptide (iRGD). iRGD peptide binds to alphav-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG2000-iRGD can be used for drug delivery[1].

[CRGDKGPDC (Disulfide bridge:Cys1-Cys9)]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]

-20°C

12131703