dTAG-13

Biorbyt

dTAG-13 [2064175-41-1]

10

2064175-41-1

Research Use Only

C57H68N4O15

1049.184

FKBP12 PROTAC dTAG-13 (dTAG-13) is an in vivo-active heterobifunctional adation tag (dTAG) small molecule that engage FKBP12F36V and CRBN, selectively degrade FKBP12F36V in a CRBN-dependent manner in cells.

N(C(=O)[C@@H](C1=CC(OC)=C(OC)C(OC)=C1)CC)1CCCC[C@@H]1C(O[C@H](C1=CC=CC=C1OCC(NCCCCCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O)=O)CCC1=CC=C(OC)C(OC)=C1)=O

12352200