The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA114923(DTX1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA114923(DTX1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
DTX1 Antibody
CSB-PA114923
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetDTX1
Overview
- SupplierCusabio
- Product NameDTX1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1840
- Target nameDTX1
- Target descriptiondeltex E3 ubiquitin ligase 1
- Target synonymsdeltex 1, E3 ubiquitin ligase; deltex homolog 1; E3 ubiquitin-protein ligase DTX1; hDx-1; protein deltex-1; RING-type E3 ubiquitin transferase DTX1; RNF140
- HostRabbit
- IsotypeIgG
- Protein IDQ86Y01
- Protein NameE3 ubiquitin-protein ligase DTX1
- Scientific DescriptionProtein deltex-1 is a protein that in humans is encoded by the DTX1 gene. Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity. DTX1 has been shown to interact with EP300. Functions as an ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203