DU-14 [186303-55-9]

MedChem Express

DU-14 [186303-55-9]

5

186303-55-9

Research Use Only

99.18

C22H38N2O4S

426.61

DU-14 is a potent steroid sulfatase inhibitor with an IC50 of 55.8 nM. DU-14 inhibits the MCF-7 cell proliferation (IC50 = 38.7 nM). DU-14 has neuroprotective effects against neurotoxic Abeta, suggesting that up-regulation of endogenous DHEAS by DU-14 could be beneficial to the alleviation of Abeta-induced impairments in spatial memory and synaptic plasticity[1][2][3].

CCCCCCCCCCCCCC(NCCC1=CC=C(C=C1)OS(N)(=O)=O)=O

-20°C

12352200