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Expression of anti-BCMA CAR in Dual Epitope Anti-BCMA CAR-T Cells.
Expression of anti-BCMA CAR in Dual Epitope Anti-BCMA CAR-T Cells.
Expression of anti-BCMA CAR in Dual Epitope Anti-BCMA CAR-T Cells.

Dual Epitope Anti-BCMA CAR-T Cells

Research Use Only
78790
BPS Bioscience
Product group (Cell) Culture
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    Dual Epitope Anti-BCMA CAR-T Cells
  • Delivery Days Customer
    7
  • Applications
    Other Application
  • Certification
    Research Use Only
  • Scientific Description
    The Dual Epitope Anti-BCMA CAR-T Cells are generated via high-titer lentiviral transduction of human primary CD4+ and CD8+ T cells with the SIN Anti-BCMA CAR Lentivirus (VHH1/VHH2 ScFv-CD8-4-1BB-CD3aeta) (#78783). These ready-to use CAR (chimeric antigen receptor)-T cells express an anti-BCMA CAR consisting of a ScFv (single-chain variable fragment) that recognizes two BCMA epitopes (VHH1 and VHH2) linked to a CD8 hinge and transmembrane domains, and the 4-1BB and CD3aeta signaling domains. These CAR-T cells have been validated by flow cytometry (to determine the CAR expression) and in co-culture cytotoxicity assays.
  • Storage Instruction
    Liquid Nitrogen
  • UNSPSC
    12352207