DUOX1 antibody [N1N3]
GTX119160
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetDUOX1
Overview
- SupplierGeneTex
- Product NameDUOX1 antibody [N1N3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID53905
- Target nameDUOX1
- Target descriptiondual oxidase 1
- Target synonymsLNOX1, NOXEF1, THOX1, dual oxidase 1, NADPH thyroid oxidase 1, flavoprotein NADPH oxidase, large NOX 1, long NOX 1, nicotinamide adenine dinucleotide phosphate oxidase, thyroid oxidase 1
- HostRabbit
- IsotypeIgG
- Protein IDQ9NRD9
- Protein NameDual oxidase 1
- Scientific DescriptionThe protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Mota M, Metge BJ, Hinshaw DC, et al. Merlin deficiency alters the redox management program in breast cancer. Mol Oncol. 2021,15(4):942-956. doi: 10.1002/1878-0261.12896Read this paper
- Seimetz M, Sommer N, Bednorz M, et al. NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD. Nat Metab. 2020,2(6):532-546. doi: 10.1038/s42255-020-0215-8Read this paper
- Jafari N, Kim H, Park R, et al. CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells. PLoS One. 2017,12(1):e0170327. doi: 10.1371/journal.pone.0170327Read this paper






