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DUOX1 antibody [N1N3]

GTX119160
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetDUOX1
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Overview

  • Supplier
    GeneTex
  • Product Name
    DUOX1 antibody [N1N3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID53905
  • Target name
    DUOX1
  • Target description
    dual oxidase 1
  • Target synonyms
    LNOX1, NOXEF1, THOX1, dual oxidase 1, NADPH thyroid oxidase 1, flavoprotein NADPH oxidase, large NOX 1, long NOX 1, nicotinamide adenine dinucleotide phosphate oxidase, thyroid oxidase 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NRD9
  • Protein Name
    Dual oxidase 1
  • Scientific Description
    The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mota M, Metge BJ, Hinshaw DC, et al. Merlin deficiency alters the redox management program in breast cancer. Mol Oncol. 2021,15(4):942-956. doi: 10.1002/1878-0261.12896
    Read this paper
  • Seimetz M, Sommer N, Bednorz M, et al. NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD. Nat Metab. 2020,2(6):532-546. doi: 10.1038/s42255-020-0215-8
    Read this paper
  • Jafari N, Kim H, Park R, et al. CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells. PLoS One. 2017,12(1):e0170327. doi: 10.1371/journal.pone.0170327
    Read this paper