DUOX1 Polyclonal Antibody

Reddot Biotech

DUOX1 Polyclonal Antibody

5

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

DUOX1

dual oxidase 1

LNOX1, NOXEF1, THOX1, dual oxidase 1, NADPH thyroid oxidase 1, flavoprotein NADPH oxidase, large NOX 1, long NOX 1, nicotinamide adenine dinucleotide phosphate oxidase, thyroid oxidase 1

Rabbit

IgG

Dual oxidase 1

The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. - This is a DUOX1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

-20°C

41116161