DuP 747 (hydrochloride) [115904-74-0]

MedChem Express

DuP 747 (hydrochloride) [115904-74-0]

9

115904-74-0

Research Use Only

C24H29Cl3N2O2

483.86

DuP 747 hydrochloride is an analgesic with selective kappa-opioid receptor agonist activity. DuP 747 showed less spiradoline-appropriate selection when administered SC, but showed a partial generalized response to spiradoline when administered IP or PO. The 5-hydroxy-desmethoxy metabolite of DuP 747 induced selection of the saline-appropriate lever only. The effects of DuP 747 suggest that its metabolites may play a major role in the similar responses to spiradoline after IP and PO administration[1].

ClC(C=C1CC(N([C@H]2C3=CC=CC(OC)=C3CC[C@@H]2N4CCCC4)C)=O)=C(C=C1)Cl.Cl

12352200