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DUSP26 antibody [N1C1]

Research Use Only
GTX109283
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDUSP26
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Overview

  • Supplier
    GeneTex
  • Product Name
    DUSP26 antibody [N1C1]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.52 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID78986
  • Target name
    DUSP26
  • Target description
    dual specificity phosphatase 26
  • Target synonyms
    DSP-4; dual specificity phosphatase 26 (putative); dual specificity phosphatase SKRP3; dual specificity protein phosphatase 26; DUSP24; LDP4; LDP-4; low-molecular-mass dual-specificity phosphatase 4; MAP kinase phosphatase 8; mitogen-activated protein kinase phosphatase 8; MKP8; MKP-8; NATA1; NEAP; neuroendocrine-associated phosphatase; Novel amplified gene in thyroid anaplastic cancer; SKRP3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9BV47
  • Protein Name
    Dual specificity protein phosphatase 26
  • Scientific Description
    Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Dusp26 phosphatase regulates mitochondrial respiration and oxidative stress and protects neuronal cell death. Eroglu B et al., 2022 Mar 21, Cell Mol Life Sci
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  • Dual-specificity phosphatase 15 (DUSP15) in the nucleus accumbens is a novel negative regulator of morphine-associated contextual memory. Qiao X et al., 2021 Jan, Addict Biol
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  • NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish. Yang CH et al., 2017 Jul 12, Sci Rep
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  • The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth. Kim H et al., 2014, Nat Commun
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