DUSP26 antibody [N1C1]
GTX109283
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDUSP26
Overview
- SupplierGeneTex
- Product NameDUSP26 antibody [N1C1]
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.52 mg/ml
- ConjugateUnconjugated
- Gene ID78986
- Target nameDUSP26
- Target descriptiondual specificity phosphatase 26
- Target synonymsDSP-4; dual specificity phosphatase 26 (putative); dual specificity phosphatase SKRP3; dual specificity protein phosphatase 26; DUSP24; LDP4; LDP-4; low-molecular-mass dual-specificity phosphatase 4; MAP kinase phosphatase 8; mitogen-activated protein kinase phosphatase 8; MKP8; MKP-8; NATA1; NEAP; neuroendocrine-associated phosphatase; Novel amplified gene in thyroid anaplastic cancer; SKRP3
- HostRabbit
- IsotypeIgG
- Scientific DescriptionInactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Dusp26 phosphatase regulates mitochondrial respiration and oxidative stress and protects neuronal cell death. Eroglu B et al., 2022 Mar 21, Cell Mol Life SciRead more
- Dual-specificity phosphatase 15 (DUSP15) in the nucleus accumbens is a novel negative regulator of morphine-associated contextual memory. Qiao X et al., 2021 Jan, Addict BiolRead more
- NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish. Yang CH et al., 2017 Jul 12, Sci RepRead more
- The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth. Kim H et al., 2014, Nat CommunRead more