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Western Blot analysis of Jurkat cell and Human fetal kidney tissue using MKP-3 Polyclonal Antibody at dilution of 1:450
Western Blot analysis of Jurkat cell and Human fetal kidney tissue using MKP-3 Polyclonal Antibody at dilution of 1:450
Western Blot analysis of Jurkat cell and Human fetal kidney tissue using MKP-3 Polyclonal Antibody at dilution of 1:450

DUSP6 Polyclonal Antibody

E-AB-10308
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    DUSP6 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA WB IHC
  • Certification
    Research Use Only
  • Concentration
    0.4mg/ml
  • Scientific Description
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
  • UNSPSC
    12352203