Dxd-d5

MedChem Express

Dxd-d5

10

Research Use Only

98.84

C26H19D5FN3O6

498.51

Dxd-d 5 is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 microM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) [1].

O=C1[C@](O)(C(C([2H])([2H])[2H])([2H])[2H])C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5NC(CO)=O)C(C)=C(F)C=C6N=C4C3=C2)=O

2°C to 8°C

12352200