Dxd

AbMole BioScience

Dxd

9

1599440-33-1

Chemical

Research Use Only

493.48

Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 uM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

CCC1(O)C(=O)OCC2=C1C=C3N(CC4=C5C(CCC6=C5C(=CC(=C6C)F)N=C34)NC(=O)CO)C2=O

-20°C, sealed

12352200