DXO Antibody

Cusabio

DXO Antibody

20

ImmunoFluorescence, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Ribonuclease that specifically degrades pre-mRNAs with a defective 5\ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5\-3\ exonuclease activities. Has decapping activity toward incomplete 5\ end cap mRNAs such as unmethylated 5\ end-capped RNA to release GpppN and 5\ end monophosphate RNA. The 5\ end monophosphate RNA is then degraded by the 5\-3\ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5\-pyrophosphohydrolase activity by hydrolyzing the 5\ end triphosphate to release pyrophosphates (By similarity).

Human

-20°C or -80°C

12352203