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DYNC1LI1 antibody

GTX120114
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetDYNC1LI1
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Overview

  • Supplier
    GeneTex
  • Product Name
    DYNC1LI1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID51143
  • Target name
    DYNC1LI1
  • Target description
    dynein cytoplasmic 1 light intermediate chain 1
  • Target synonyms
    cytoplasmic dynein 1 light intermediate chain 1; DLC-A; DNCLI1; dynein light chain A; dynein light intermediate chain 1, cytosolic; dynein, cytoplasmic, light intermediate polypeptide 1; LIC1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y6G9
  • Protein Name
    Cytoplasmic dynein 1 light intermediate chain 1
  • Scientific Description
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CENP-E activation by Aurora A and B controls kinetochore fibrous corona disassembly.
    Read more
  • Microtubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congression.
    Read more
  • Targeting long noncoding RNA PMIF facilitates osteoprogenitor cells migrating to bone formation surface to promote bone formation during aging. Li D et al., 2021, Theranostics
    Read more
  • The mitotic tensegrity guardian tau protects mammary epithelia from katanin-like1-induced aneuploidy. Sudo H et al., 2016 Aug 16, Oncotarget
    Read more
  • Resources for the Comprehensive Discovery of Functional RNA Elements. Sundararaman B et al., 2016 Mar 17, Mol Cell
    Read more
  • Gene targets of mouse miR-709: regulation of distinct pools. Surendran S et al., 2016 Jan 8, Sci Rep
    Read more
  • POPX2 phosphatase regulates cell polarity and centrosome placement. Hoon JL et al., 2014, Cell Cycle
    Read more

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