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DYNC1LI1 antibody

Name: DYNC1LI1 antibody
SKU: GTX120114_G10
Availability: BackOrder

GTX120114

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetDYNC1LI1

Overview

Supplier
GeneTex
Product Name
DYNC1LI1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID51143
Target name
DYNC1LI1
Target description
dynein cytoplasmic 1 light intermediate chain 1
Target synonyms
DLC-A, DLIC-1, DNCLI1, LIC1, cytoplasmic dynein 1 light intermediate chain 1, dynein light chain A, dynein light intermediate chain 1, cytosolic, dynein, cytoplasmic, light intermediate polypeptide 1
Host
Rabbit
Isotype
IgG
Protein IDQ9Y6G9
Protein Name
Cytoplasmic dynein 1 light intermediate chain 1
Scientific Description
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Eibes S, Rajendraprasad G, Guasch-Boldu C, et al. CENP-E activation by Aurora A and B controls kinetochore fibrous corona disassembly. Nat Commun. 2023,14(1):5317. doi: 10.1038/s41467-023-41091-2
Read this paper
Wu J, Larreategui-Aparicio A, Lambers MLA, et al. Microtubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congression. Curr Biol. 2023,33(5):912-925.e6. doi: 10.1016/j.cub.2023.01.010
Read this paper
Li D, Liu J, Yang C, et al. Targeting long noncoding RNA PMIF facilitates osteoprogenitor cells migrating to bone formation surface to promote bone formation during aging. Theranostics. 2021,11(11):5585-5604. doi: 10.7150/thno.54477
Read this paper
Sudo H, Nakajima K. The mitotic tensegrity guardian tau protects mammary epithelia from katanin-like1-induced aneuploidy. Oncotarget. 2016,7(33):53712-53734. doi: 10.18632/oncotarget.10728
Read this paper
Sundararaman B, Zhan L, Blue SM, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016,61(6):903-13. doi: 10.1016/j.molcel.2016.02.012
Read this paper
Surendran S, Jideonwo VN, Merchun C, et al. Gene targets of mouse miR-709: regulation of distinct pools. Sci Rep. 2016,6:18958. doi: 10.1038/srep18958
Read this paper
Hoon JL, Li HY, Koh CG. POPX2 phosphatase regulates cell polarity and centrosome placement. Cell Cycle. 2014,13(15):2459-68. doi: 10.4161/cc.29421
Read this paper

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DYNC1LI1 antibody

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