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The data was published in the journal Front Oncol in 2019. PMID: 31024851
The data was published in the journal Front Oncol in 2019. PMID: 31024851
The data was published in the journal Front Oncol in 2019. PMID: 31024851

Dynein antibody [74.1]

GTX80684
GeneTex
TargetDYNLL1
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    Dynein antibody [74.1]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody detects two isoforms of the ~74 kDa polypetide of cytoplasmic dynein.
  • Application Supplier Note
    WB: 1 microg/ml. ICC/IF: 2-4 microg/ml. FACS: 1-2 microg/test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Clone ID
    74.1
  • Concentration
    1 mg/ml
  • Formulation
    Liquid
  • Gene ID404151
  • Target name
    DYNLL1
  • Target description
    dynein light chain LC8-type 1
  • Target synonyms
    CDLC2; cytoplasmic dynein light polypeptide; DNCL1; dynein light chain 1, cytoplasmic
  • Protein IDP61285
  • Protein Name
    Dynein light chain 1, cytoplasmic
  • Scientific Description
    The directed movement of membrane-bounded organelles is an important process for various cellular functions including membrane transport, secretion, and axonal transport. Cytoplasmic dynein, a ubiquitous minus end-directed microtubule-based motor protein, is believed to be responsible for the retrograde transport of membranous organelles from the synapse to the cell body in fast axonal transport. The cytoplasmic dynein complex is composed of two ~530 kDa heavy chains, and intermediate chains of ~74 kDa and ~53-59 kDa.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • MPT0G413, A Novel HDAC6-Selective Inhibitor, and Bortezomib Synergistically Exert Anti-tumor Activity in Multiple Myeloma Cells. Huang FI et al., 2019, Front Oncol
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