Dynein Intermediate chain antibody [70.1]

GeneTex

Dynein Intermediate chain antibody [70.1]

9

WB: 1:500~1:2,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Electron Microscopy, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Monoclonal

70.1

Unconjugated

DNAI1

dynein axonemal intermediate chain 1

dynein intermediate chain 1, axonemal, dynein axonemal intermediate chain 1

Mouse

IgM

Eukaryotic cells rely on actin and microtubule-based protein motors to generate intracellular movements (4). These protein motors contain specialized domains that hydrolyze ATP to produce force and movement along a cytoskeletal polymer (actin in the case of myosin family and microtubules in the case of the kinesin family and dyneins). Dynein has been implicated in cytoplasmic motile functions, including chromosomal movement, retrograde organelle and axonal transport, the endocytic pathway, and the organization of the Golgi apparatus. In all cell types, dynein has the same basic structures and is composed of two or three distinct heavy chains (~450 kD), three intermediate chains (70-125 kD), and at least four light chains (15-25 kD) (5).

Amphibian, Chicken, Hamster, Human, Mammals, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203