Dynole 34-2

MedChem Express

Dynole 34-2 [1128165-88-7]

10

1128165-88-7

Research Use Only

98.16

C25H36N4O

408.58

Dynole 34-2 is a potent dynamin GTPase inhibitor ( IC 50 s=6.9 and 14.2 microM for dynamin1 and dynamin2 GTPase activity, respectively) with antimitotic effect. Dynole 34-2 induces apoptosis , as revealed by cell blebbing, DNA fragmentation, and PARP cleavage. Dynole 34-2 also potently inhibits receptor mediated endocytosis (RME) [1] [2] .

N#C/C(C(NCCCCCCCC)=O)=C\C1=CN(CCCN(C)C)C2=C1C=CC=C2

2°C to 8°C

12352200