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(E)-2-Hexadecenal [22644-96-8]

HY-121683
MedChem Express
CAS Number22644-96-8
Product group Chemicals
Molecular Weight238.41
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Overview

  • Supplier
    MedChem Express
  • Product Name
    (E)-2-Hexadecenal [22644-96-8]
  • Delivery Days Customer
    5
  • CAS Number
    22644-96-8
  • Certification
    Research Use Only
  • Molecular Formula
    C16H30O
  • Molecular Weight
    238.41
  • Scientific Description
    (E)-2-Hexadecenal (trans-2-Hexadecenal) is an MLK3 activator that induces cytoskeletal remodeling, leading to cell rounding, detachment, and ultimately apoptosis in human and mouse cells. (E)-2-Hexadecenal activates the MLK3 signaling pathway, phosphorylating MKK4/7 and JNK, subsequently activating downstream targets of JNK, such as c-Jun phosphorylation, cytochrome c release, Bax activation, Bid cleavage, and Bim translocation to mitochondria. (E)-2-Hexadecenal has potential applications in research related to sphingolipid signaling pathways[1].
  • SMILES
    CCCCCCCCCCCCC/C=C/C=O
  • UNSPSC
    12352200