(E)-3,4,5-Trimethoxycinnamic acid [20329-98-0]

MedChem Express

(E)-3,4,5-Trimethoxycinnamic acid [20329-98-0]

10

20329-98-0

Research Use Only

99.97

C12H14O5

238.24

(E)-3,4,5-Trimethoxycinnamic acid (TMCA) is a cinnamic acid substituted by multi-methoxy groups. (E)-3,4,5-Trimethoxycinnamic acid is an orally active and potent GABAA/BZ receptor agonist. (E)-3,4,5-Trimethoxycinnamic exhibits favourable binding affinity to 5-HT2C and 5-HT1A receptor, with IC50 values of 2.5 and 7.6 microM, respectively. (E)-3,4,5-Trimethoxycinnamic acid shows anticonvulsant and sedative activity. (E)-3,4,5-Trimethoxycinnamic acid can be used for the research of insomnia, headache and epilepsy[1][2][3].

O=C(O)/C=C/C1=CC(OC)=C(OC)C(OC)=C1

-20°C,2°C to 8°C

12352200